Josef Spacek, MUDr., DrSc.  

Josef Spacek, MUDr., DrSc.

Professor of Pathology

Charles University Medical Faculty
Hradec Kralove, Czech Republic

Research Interests:

Dr. Spacek has done research in neurobiological systems for more than thirty years. Although he studied Medicine and is specialized in surgical pathology and diagnostic electron microscopy, he has been keenly interested in neurological ultrastructure and three-dimensional reconstruction since his days as a medical student. In 1971 he published "Three-dimensional reconstructions of astroglia and oligodendroglia cells" in Z. Zellforsch which was among the first reconstructionsJosef Spacek, MUDr., DrSc. of neural ultrastructure. His career has included fellowships in the laboratory of Prof. E. G. Gray, University College, London and a collaboration with Prof. A. R. Lieberman, University College, London and Editor of the Journal of Neurocytology. In recent years he has collaborated with Dr. Kristen Harris, and produced the Atlas of Ultrastructural Neurocytology on this site.

This collaboration has produced significant insights into the three-dimensional organization of neural components.

Selected Publications:

  • Spacek J, Harris KM. (1998) Three-Dimensional Organization of Cell Adhesion Junctions at Synapses and Dendritic Spines in Area CA1 of the Rat Hippocampus. J. Comp. Neurol. 393:58-68.
  • Spacek J, Harris KM. (1997) Three-Dimensional Organization of Smooth Endoplasmic Reticulum in Hippocampal CA1 Dendrites and Dendritic Spines of the Immature and Mature Rat. J.Neurosci. 17 (1):190-203.
  • J. Spacek (1982) Ribosome-associated Membrane Contacts Between Astrocytes In Anoxic Brain. Acta Neuropathol (Berl). 57:270-274. (1,791Kb PDF)
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